phenobarbital sodium contraindications for Dummies
phenobarbital sodium contraindications for Dummies
Blog Article
benzhydrocodone/acetaminophen and pentobarbital each boost sedation. Stay away from or Use Alternate Drug. Limit use to individuals for whom alternative treatment method selections are insufficient
pentobarbital will decrease the level or effect of vinorelbine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unidentified.
pentobarbital will reduce the level or effect of tinidazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will minimize the level or effect of prednisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lessen the level or effect of midostaurin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Solid CYP3A4 inducers might reduce midostaurin concentrations resulting in lessened efficacy.
pentobarbital will lessen the level or effect of armodafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Mysterious.
pentobarbital will reduce the extent or effect of methadone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will decrease the extent or effect of sufentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.
pentobarbital will reduce the level or effect of pitolisant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Pitolisant exposure is diminished by 50% if coadministered with robust CYP3A4 inducers.
Geriatric use: Scientific experiments of Nembutal haven't integrated enough numbers of subjects aged 65 and over to pentobarbital sodium brand name find out irrespective of whether aged subjects reply in a different way from young subjects. Other reported scientific knowledge hasn't discovered dissimilarities in responses between the aged and young patients. Generally speaking, dose variety for an aged affected individual ought to be cautious, typically starting off on the low end of the dosing variety, reflecting the higher frequency of decreased hepatic, renal or cardiac function, and of concomitant sickness or other drug therapy.
pentobarbital will lower the level or effect of lapatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will reduce the level or effect of bosentan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.
pentobarbital will lower the extent or effect of cobimetinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid coadministration. Strong or average CYP3A inducers may possibly lower cobimetinib systemic publicity by >80% and reduce its efficacy.
pentobarbital will decrease the level or effect of carbamazepine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.